Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

12 papers

NM_005427.4

p.T5I

c.14C>T

Surrounding Variants

3 papers

NM_005427.4

p.T7I

c.20C>T

1 paper

NM_005427.4

p.S8Fs

c.22delinsTTFs

15 papers

NM_005427.4

p.A2T

c.4G>A

1 paper

NM_005427.4

p.A2P

c.4G>C

1 paper

NM_005427.4

p.M1I

c.3G>A

1 paper

NM_005427.4

p.D10E

c.30T>A

1 paper

NM_005427.4

p.G11V

c.32G>T

1 paper

NM_005427.4

p.G12S

c.34G>A

2 papers

NM_005427.4

p.G12D

c.35G>A

1 paper

NM_005427.4

p.G12V

c.35G>T

1 paper

NM_005427.4

p.T13I

c.38C>T

2 papers

NM_005427.4

p.T14M

c.41C>T