Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_005427.4

p.L54R

c.161T>G

Surrounding Variants

2 papers

NM_005427.4

p.H53L

c.158A>T

1 paper

NM_005427.4

p.M57K

c.170T>A

1 paper

NM_005427.4

p.V51I

c.151G>A

1 paper

NM_005427.4

p.T45A

c.133A>G

1 paper

NM_005427.4

p.G44R

c.130G>A

1 paper

NM_005427.4

p.G44R

c.130G>C

1 paper

NM_005427.4

p.E40G

c.119A>G

1 paper

NM_005427.4

p.N39D

c.115A>G

1 paper

NM_005427.4

p.R36Q

c.107G>A

1 paper

NM_005427.4

p.R36P

c.107G>C

1 paper

NM_005427.4

p.S35N

c.104G>A

1 paper

NM_005427.4

p.S34*

c.101C>A