Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005427.4

p.A90T

c.268G>A

Surrounding Variants

1 paper

NM_005427.4

p.E88E

c.264G>A

1 paper

NM_005427.4

p.E88_A90delFs

c.264_268del5

2 papers

NM_005427.4

p.V93M

c.277G>A

1 paper

NM_005427.4

p.P87_A91delFs

c.259_272del14

1 paper

NM_005427.4

p.S83R

c.249C>A

1 paper

NM_005427.4

p.S83R

c.249C>G

1 paper

NM_005427.4

p.S83R

c.247A>C

1 paper

NM_005427.4

p.S97S

c.291G>A

1 paper

NM_005427.4

p.S81_A82insFs

c.243_244insT

1 paper

NM_005427.4

p.A80V

c.239C>T

1 paper

NM_005427.4

p.A79V

c.236C>T

1 paper

NM_001126240.3

p.A30T

c.88G>A