Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005427.4

p.P116L

c.347C>T

Surrounding Variants

1 paper

NM_005427.4

p.P116S

c.346C>T

1 paper

NM_005427.4

p.S117P

c.349T>C

1 paper

NM_005427.4

p.I115delFs

c.344_345delTC

1 paper

NM_005427.4

p.V114V

c.342C>A

1 paper

NM_005427.4

p.D120G

c.359A>G

1 paper

NM_005427.4

p.A112V

c.335C>T

1 paper

NM_005427.4

p.P111L

c.332C>T

2 papers

NM_005427.4

p.S110L

c.329C>T

1 paper

NM_005427.4

p.T108delFs

c.323delC

3 papers

NM_005427.4

p.P124P

c.372C>T

1 paper

NM_005427.4

p.S104F

c.311C>T

1 paper

NM_005427.4

p.P102P

c.306C>T