Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_005427.4

p.T136M

c.407C>T

NM_001126240.3

p.T87M

c.260C>T

Surrounding Variants

1 paper

NM_005427.4

p.K138*

c.412A>T

1 paper

NM_005427.4

p.Q133delins

c.397_398delinsAC

1 paper

NM_005427.4

p.T143S

c.427A>T

1 paper

NM_005427.4

p.T143M

c.428C>T

3 papers

NM_005427.4

p.P124P

c.372C>T

1 paper

NM_005427.4

p.D120G

c.359A>G

1 paper

NM_005427.4

p.S117P

c.349T>C

1 paper

NM_005427.4

p.P116L

c.347C>T

1 paper

NM_005427.4

p.P116S

c.346C>T

1 paper

NM_005427.4

p.I115delFs

c.344_345delTC

1 paper

NM_005427.4

p.V114V

c.342C>A

1 paper

NM_005427.4

p.A112V

c.335C>T