Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005427.4

p.V217M

c.649G>A

Surrounding Variants

3 papers

NM_005427.4

p.N220S

c.659A>G

1 paper

NM_005427.4

p.N221Y

c.661A>T

1 paper

NM_005427.4

p.A211S

c.631G>T

2 papers

NM_005427.4

p.P210L

c.629C>T

1 paper

NM_005427.4

p.Q224P

c.671A>C

1 paper

NM_005427.4

p.D227_R233ins2

c.679_699dup21

1 paper

NM_005427.4

p.V230A

c.689T>C

1 paper

NM_005427.4

p.V236I

c.706G>A

NM_001126240.3

p.V187I

c.559G>A

1 paper

NM_005427.4

p.P239S

c.715C>T

1 paper

NM_005427.4

p.P239L

c.716C>T

1 paper

NM_005427.4

p.Q244K

c.730C>A

1 paper

NM_005427.4

p.G206Splc

c.617-275T>C