Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005427.4

p.R288Q

c.863G>A

Surrounding Variants

1 paper

NM_005427.4

p.R288W

c.862C>T

2 papers

NM_005427.4

p.E291K

c.871G>A

1 paper

NM_005427.4

p.G292D

c.875G>A

1 paper

NM_005427.4

p.R293H

c.878G>A

1 paper

NM_005427.4

p.Q283K

c.847C>A

1 paper

NM_005427.4

p.C295delFs

c.885delC

2 papers

NM_005427.4

p.G299V

c.896G>T

1 paper

NM_005427.4

p.R300L

c.899G>T

1 paper

NM_005427.4

p.R302Q

c.905G>A

3 papers

NM_005427.4

p.R310Q

c.929G>A

NM_001126240.3

p.R261Q

c.782G>A

1 paper

NM_005427.4

p.E311A

c.932A>C

1 paper

NM_005427.4

p.A314T

c.940G>A