Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005427.4

p.E376D

c.1128G>C

Surrounding Variants

1 paper

NM_005427.4

p.E376D

c.1128G>T

3 papers

NM_005427.4

p.L380V

c.1138T>G

NM_001126240.3

p.L331V

c.991T>G

3 papers

NM_005427.4

p.L371P

c.1112T>C

1 paper

NM_005427.4

p.V386A

c.1157T>C

1 paper

NM_005427.4

p.F365L

c.1095T>A

1 paper

NM_005427.4

p.F365L

c.1095T>G

1 paper

NM_005427.4

p.F365L

c.1093T>C

4 papers

NM_005427.4

p.R362Q

c.1085G>A

NM_001126240.3

p.R313Q

c.938G>A

3 papers

NM_005427.4

p.Q391R

c.1172A>G

NM_001126240.3

p.Q342R

c.1025A>G

2 papers

NM_005427.4

p.R362W

c.1084C>T

2 papers

NM_005427.4

p.Q392E

c.1174C>G

NM_001126240.3

p.Q343E

c.1027C>G

1 paper

NM_005427.4

p.Q392R

c.1175A>G