Varaico: Literature-Extracted Genetic Variants

TP73

342 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neu...

Pfam Domains

P53aa 117–309UCSCP53 DNA-binding domain

P53_tetrameraa 345–385UCSCP53 tetramerisation motif

Gene Aliases

HGNC Name

tumor protein p73

HGNC Alias Symbol

P73

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_005427.4

p.P425L

c.1274C>T

Surrounding Variants

1 paper

NM_005427.4

p.S426S

c.1278C>T

2 papers

NM_005427.4

p.V427I

c.1279G>A

1 paper

NM_005427.4

p.K423del1

c.1267_1268delAAG

1 paper

NM_005427.4

p.L430M

c.1288C>A

1 paper

NM_005427.4

p.G419R

c.1255G>A

1 paper

NM_005427.4

p.G419R

c.1255G>C

1 paper

NM_005427.4

p.H418H

c.1254C>T

1 paper

NM_005427.4

p.P436fs

c.1306_1307fs

2 papers

NM_005427.4

p.S439L

c.1316C>T

NM_001126240.3

p.S390L

c.1169C>T

1 paper

NM_005427.4

p.A440V

c.1319C>T

1 paper

NM_005427.4

p.A441P

c.1321G>C

1 paper

NM_005427.4

p.P409L

c.1226C>T