Varaico: Literature-Extracted Genetic Variants

TPBG

35 papers

RefSeq Summary

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this pro...

Pfam Domains

LRRNTaa 61–90UCSCLeucine rich repeat N-terminal domain

LRR_8aa 91–154UCSCLeucine rich repeat

LRR_8aa 210–270UCSCLeucine rich repeat

LRRCTaa 320–345UCSCLeucine rich repeat C-terminal domain

Gene Aliases

HGNC Name

trophoblast glycoprotein

HGNC Alias Symbols

5T4-AG; 5T4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001376922.1

p.S69A

c.205T>G

Surrounding Variants

1 paper

NM_001376922.1

p.E67A

c.200A>C

1 paper

NM_001376922.1

p.Q61K

c.181C>A

1 paper

NM_001376922.1

p.P86H

c.257C>A

1 paper

NM_001376922.1

p.T87A

c.259A>G

1 paper

NM_001376922.1

p.F47V

c.139T>G

1 paper

NM_001376922.1

p.P46fs

c.136_137fs

1 paper

NM_001376922.1

p.P46S

c.136C>T

1 paper

NM_001376922.1

p.N101H

c.301A>C

1 paper

NM_001376922.1

p.S37P

c.109T>C

1 paper

NM_001376922.1

p.L106P

c.317T>C

1 paper

NM_001376922.1

p.S31W

c.92C>G

1 paper

NM_001376922.1

p.P116_A122delFs

c.347_365del19