Varaico: Literature-Extracted Genetic Variants

Gene:TPH2
Variant:p.L77F

TPH2

354 papers

RefSeq Summary

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormo...

Pfam Domains

Biopterin_Haa 152–482UCSCBiopterin-dependent aromatic amino acid hydroxylase

Gene Aliases

HGNC Name

tryptophan hydroxylase 2

HGNC Alias Symbols

NTPH; FLJ37295

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_173353.4
p.L77F
c.231G>T
Surrounding Variants
1 paper
NM_173353.4
p.L77F
c.231G>C
1 paper
NM_173353.4
p.V78I
c.232G>A
4 papers
NM_173353.4
p.G75S
c.223G>A
1 paper
NM_173353.4
p.E73D
c.219A>C
39 papers
NM_173353.4
p.E73A
c.218A>C
1 paper
NM_173353.4
p.R82R
c.246G>A
1 paper
NM_173353.4
p.R82S
c.246G>C
1 paper
NM_173353.4
p.R82S
c.246G>T
1 paper
NM_173353.4
p.L83V
c.247C>G
1 paper
NM_173353.4
p.F84Y
c.251T>A
1 paper
NM_173353.4
p.Q85_E86Splc
c.255+1G>A
1 paper
NM_173353.4
p.V67A
c.200T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."