Varaico: Literature-Extracted Genetic Variants

Gene:TPM3
Variant:p.R245G

TPM3

394 papers

RefSeq Summary

This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other a...

Pfam Domains

Tropomyosinaa 2–84UCSCTropomyosin
Tropomyosinaa 2–84UCSCTropomyosin

Gene Aliases

HGNC Name

tropomyosin 3

HGNC Previous Symbol

NEM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
19 papers
NM_152263.4
p.R245G
c.733A>G
Surrounding Variants
3 papers
NM_152263.4
p.R245I
c.734G>T
2 papers
NM_152263.4
p.E244D
c.732G>T
2 papers
NM_152263.4
p.R245T
c.734G>C
2 papers
NM_152263.4
p.E244D
c.732G>C
1 paper
NM_152263.4
p.R245delFs
c.734_735delTC
1 paper
NM_152263.4
p.S246L
c.737C>T
1 paper
NM_152263.4
p.S246S
c.738G>A
1 paper
NM_152263.4
p.A243T
c.727G>A
1 paper
NM_152263.4
p.A248T
c.742G>A
1 paper
NM_152263.4
p.E241G
c.722A>G
7 papers
NM_152263.4
p.E241K
c.721G>A
1 paper
NM_152263.4
p.R239C
c.715C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."