Varaico: Literature-Extracted Genetic Variants

TPR

566 papers

RefSeq Summary

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components o...

Pfam Domains

Nucleoprot-TPRaa 171–252UCSCNucleoprotein TPR-like domain

TPRaa 471–569UCSCNucleoprotein TPR-like domain

TPR_MLP1_2aa 1038–1166UCSCTPR/MLP1/MLP2-like protein

Gene Aliases

HGNC Name

translocated promoter region, nuclear basket protein

HGNC Previous Name

translocated promoter region (to activated MET oncogene)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003292.3

p.Q110_S111Splc

c.331-2A>G

Surrounding Variants

5 papers

NM_003292.3

p.Q110_S111Splc

c.331-1G>A

1 paper

NM_003292.3

p.Q112delFs

c.335_336delTT

2 papers

NM_003292.3

p.T114I

c.341C>T

1 paper

NM_003292.3

p.Q110_S111Splc

c.331-15T>C

1 paper

NM_003292.3

p.R115K

c.344G>A

1 paper

NM_003292.3

p.Q110_S111Splc

c.331-20A>G

1 paper

NM_003292.3

p.E118K

c.352G>A

1 paper

NM_003292.3

p.E119Q

c.355G>C

1 paper

NM_003292.3

p.E119K

c.355G>A

1 paper

NM_003292.3

p.E119V

c.356A>T

1 paper

NM_003292.3

p.E119A

c.356A>C

1 paper

NM_003292.3

p.L120delFs

c.360delT