Varaico: Literature-Extracted Genetic Variants

TRAF2

289 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF rece...

Pfam Domains

zf-C3HC4aa 34–72UCSCZinc finger, C3HC4 type (RING finger)

TRAF2_zfaa 104–122UCSCTRAF2, second zinc finger

zf-TRAFaa 178–235UCSCTRAF-type zinc finger

TRAF_BIRC3_bdaa 267–330UCSCTNF receptor-associated factor BIRC3 binding domain

TRAF-mep_MATHaa 374–493UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 2

HGNC Alias Symbols

TRAP3; RNF117

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021138.4

p.L62P

c.185T>C

Surrounding Variants

1 paper

NM_021138.4

p.C57S

c.170G>C

1 paper

NM_021138.4

p.C57S

c.169T>A

1 paper

NM_021138.4

p.R52Q

c.155G>A

1 paper

NM_021138.4

p.Q48*

c.142C>T

4 papers

NM_021138.4

p.A47V

c.140C>T

1 paper

NM_021138.4

p.A47T

c.139G>A

1 paper

NM_021138.4

p.A47S

c.139G>T

1 paper

NM_021138.4

p.R43W

c.127A>T

1 paper

NM_021138.4

p.R42H

c.125G>A

1 paper

NM_021138.4

p.C37W

c.111C>G

1 paper

NM_021138.4

p.C37Y

c.110G>A

1 paper

NM_021138.4

p.A36D

c.107C>A