Varaico: Literature-Extracted Genetic Variants

TRAF2

289 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF rece...

Pfam Domains

zf-C3HC4aa 34–72UCSCZinc finger, C3HC4 type (RING finger)

TRAF2_zfaa 104–122UCSCTRAF2, second zinc finger

zf-TRAFaa 178–235UCSCTRAF-type zinc finger

TRAF_BIRC3_bdaa 267–330UCSCTNF receptor-associated factor BIRC3 binding domain

TRAF-mep_MATHaa 374–493UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 2

HGNC Alias Symbols

TRAP3; RNF117

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_021138.4

p.D488N

c.1462G>A

Surrounding Variants

1 paper

NM_021138.4

p.R486Q

c.1457G>A

1 paper

NM_021138.4

p.I492F

c.1474A>T

1 paper

NM_021138.4

p.A494V

c.1481C>T

1 paper

NM_021138.4

p.V475I

c.1423G>A

1 paper

NM_021138.4

p.N461delFs

c.1383delC

1 paper

NM_021138.4

p.N461fs

c.1381_1382fs

1 paper

NM_021138.4

p.P459L

c.1376C>T

2 papers

NM_021138.4

p.Q457L

c.1370A>T

1 paper

NM_021138.4

p.Q457fs

c.1369_1370fs

1 paper

NM_021138.4

p.Q457*

c.1369C>T

1 paper

NM_021138.4

p.D450N

c.1348G>A

1 paper

NM_021138.4

p.R448M

c.1343G>T