Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

1–12 of 447 variants

21 papers

NM_145725.3

p.R118W

c.352C>T

8 papers

NM_145725.3

p.R310*

c.928C>T

7 papers

NM_145725.3

p.Q114*

c.340C>T

7 papers

NM_145725.3

p.Y425*

c.1275C>A

7 papers

NM_145725.3

p.Y425*

c.1275C>G

6 papers

NM_145725.3

p.R163*

c.487C>T

5 papers

NM_145725.3

p.M129T

c.386T>C

5 papers

NM_145725.3

p.R505*

c.1513C>T

4 papers

NM_145725.3

p.V240I

c.718G>A

4 papers

NM_145725.3

p.N285fs

c.853_854fs

4 papers

NM_145725.3

p.R321*

c.961C>T

4 papers

NM_145725.3

p.E431*

c.1291G>T