Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145725.3

p.C124R

c.370T>C

Surrounding Variants

1 paper

NM_145725.3

p.G123D

c.368G>A

1 paper

NM_145725.3

p.A125_Q127delFs

c.373_379del7

1 paper

NM_145725.3

p.S121I

c.362G>T

5 papers

NM_145725.3

p.M129T

c.386T>C

1 paper

NM_145725.3

p.R118P

c.353G>C

21 papers

NM_145725.3

p.R118W

c.352C>T

1 paper

NM_145725.3

p.L130P

c.389T>C

1 paper

NM_145725.3

p.G131*

c.391G>T

1 paper

NM_145725.3

p.C117R

c.349T>C

1 paper

NM_145725.3

p.Y116C

c.347A>G

1 paper

NM_145725.3

p.L133Fs

c.398delinsTAFs

7 papers

NM_145725.3

p.Q114*

c.340C>T