Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_145725.3

p.A188T

c.562G>A

Surrounding Variants

3 papers

NM_145725.3

p.A188V

c.563C>T

1 paper

NM_145725.3

p.L189_Q190delFs

c.566_569del4

1 paper

NM_145725.3

p.Q183H

c.549G>C

1 paper

NM_145725.3

p.Q183H

c.549G>T

1 paper

NM_145725.3

p.Q183R

c.548A>G

1 paper

NM_145725.3

p.Q183*

c.547C>T

1 paper

NM_145725.3

p.S178N

c.533G>A

1 paper

NM_145725.3

p.C177F

c.530G>T

1 paper

NM_145725.3

p.C177fs

c.529_530fs

1 paper

NM_145725.3

p.E174fs

c.520_521fs

1 paper

NM_145725.3

p.R173Q

c.518G>A

1 paper

NM_145725.3

p.R173G

c.517C>G