Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145725.3

p.S219C

c.655A>T

Surrounding Variants

1 paper

NM_145725.3

p.S219Fs

c.656delinsCAFs

1 paper

NM_145725.3

p.A220V

c.659C>T

1 paper

NM_145725.3

p.E217_L218Splc

c.652-7G>A

1 paper

NM_145725.3

p.E224*

c.670G>T

1 paper

NM_145725.3

p.E224_P229Fs

c.672_685delinsGFs

1 paper

NM_145725.3

p.N227I

c.680A>T

1 paper

NM_145725.3

p.A228Fs

c.682delinsGCFs

1 paper

NM_145725.3

p.S230fs

c.688_689fs

1 paper

NM_145725.3

p.C232Fs

c.694delinsGTFs

1 paper

NM_145725.3

p.C232R

c.694T>C

1 paper

NM_145725.3

p.C232*

c.696T>A

1 paper

NM_145725.3

p.F234Fs

c.702delinsCAFs