Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145725.3

p.D324fs

c.970_971fs

Surrounding Variants

2 papers

NM_145725.3

p.I323_D324delFs

c.968_971del4

1 paper

NM_145725.3

p.V322Fs

c.964_965delinsCFs

2 papers

NM_145725.3

p.R321Q

c.962G>A

4 papers

NM_145725.3

p.R321*

c.961C>T

1 paper

NM_145725.3

p.L330fs

c.988_989fs

1 paper

NM_145725.3

p.K331*

c.991A>T

1 paper

NM_145725.3

p.E332*

c.994G>T

1 paper

NM_145725.3

p.K335Fs

c.1003delinsCTGATTFs

1 paper

NM_145725.3

p.E336fs

c.1006_1007fs

1 paper

NM_145725.3

p.I337fs

c.1009_1010fs

2 papers

NM_145725.3

p.R338W

c.1012C>T

1 paper

NM_145725.3

p.P339_F340ins4

c.1015_1019ins12