Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_145725.3

p.E431*

c.1291G>T

Surrounding Variants

1 paper

NM_145725.3

p.Q430*

c.1288C>T

1 paper

NM_145725.3

p.R428Q

c.1283G>A

1 paper

NM_145725.3

p.K426fs

c.1276_1277fs

2 papers

NM_145725.3

p.K436*

c.1306A>T

7 papers

NM_145725.3

p.Y425*

c.1275C>A

7 papers

NM_145725.3

p.Y425*

c.1275C>G

1 paper

NM_145725.3

p.Y425delFs

c.1275delC

1 paper

NM_145725.3

p.T437fs

c.1309_1310fs

1 paper

NM_145725.3

p.D424N

c.1270G>A

1 paper

NM_145725.3

p.D424fs

c.1270_1271fs

1 paper

NM_145725.3

p.D424Y

c.1270G>T

1 paper

NM_145725.3

p.L438L

c.1314G>C