Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145725.3

p.Y452*

c.1356T>G

Surrounding Variants

1 paper

NM_145725.3

p.Y452*

c.1356T>A

1 paper

NM_145725.3

p.K453Q

c.1357A>C

4 papers

NM_145725.3

p.Y452C

c.1355A>G

2 papers

NM_145725.3

p.K453N

c.1359G>C

2 papers

NM_145725.3

p.K453N

c.1359G>T

1 paper

NM_145725.3

p.G451delins

c.1351delinsTGCCCAGTGA

1 paper

NM_145725.3

p.F450F

c.1350T>C

1 paper

NM_145725.3

p.F450C

c.1349T>G

2 papers

NM_145725.3

p.Y449*

c.1347C>A

2 papers

NM_145725.3

p.Y449*

c.1347C>G

1 paper

NM_145725.3

p.Y449fs

c.1345_1346fs

1 paper

NM_145725.3

p.G448V

c.1343G>T