Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_145725.3

p.R505*

c.1513C>T

Surrounding Variants

1 paper

NM_145725.3

p.R506C

c.1516C>T

1 paper

NM_145725.3

p.R506H

c.1517G>A

1 paper

NM_145725.3

p.S503fs

c.1507_1508fs

1 paper

NM_145725.3

p.G502E

c.1505G>A

4 papers

NM_145725.3

p.Q501*

c.1501C>T

1 paper

NM_145725.3

p.Q501fs

c.1501_1502fs

1 paper

NM_145725.3

p.Q501insFs

c.1501dupC

1 paper

NM_145725.3

p.D510N

c.1528G>A

2 papers

NM_145725.3

p.D500Y

c.1498G>T

1 paper

NM_145725.3

p.K513R

c.1538A>G

1 paper

NM_145725.3

p.V494G

c.1481T>G

1 paper

NM_145725.3

p.V494M

c.1480G>A