Varaico: Literature-Extracted Genetic Variants

TRAF3

301 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF rec...

Pfam Domains

TRAF3_RINGaa 53–92UCSCTNF receptor-associated factor 2/3/5, RING domain

zf-TRAFaa 136–192UCSCTRAF-type zinc finger

zf-TRAFaa 192–251UCSCTRAF-type zinc finger

TRAF-mep_MATHaa 437–557UCSCTRAF/meprin, MATH domain

Gene Aliases

HGNC Name

TNF receptor associated factor 3

HGNC Alias Symbols

CAP-1; CD40bp; CRAF1; LAP1; RNF118

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145725.3

p.P524fs

c.1570_1571fs

Surrounding Variants

1 paper

NM_145725.3

p.K523fs

c.1567_1568fs

1 paper

NM_145725.3

p.K522K

c.1566G>A

1 paper

NM_145725.3

p.K522delFs

c.1566delG

1 paper

NM_145725.3

p.G526fs

c.1576_1577fs

1 paper

NM_145725.3

p.G526G

c.1578A>G

1 paper

NM_145725.3

p.E527*

c.1579G>T

1 paper

NM_145725.3

p.S518delFs

c.1554delC

1 paper

NM_145725.3

p.S518fs

c.1552_1553fs

1 paper

NM_145725.3

p.A531insFs

c.1591_1592insTC

1 paper

NM_145725.3

p.A531V

c.1592C>T

1 paper

NM_145725.3

p.G533S

c.1597G>A

1 paper

NM_145725.3

p.G533A

c.1598G>C