Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_032271.3

p.G390E

c.1169G>A

Surrounding Variants

4 papers

NM_032271.3

p.G390R

c.1168G>A

4 papers

NM_032271.3

p.G390R

c.1168G>C

1 paper

NM_032271.3

p.T391N

c.1172C>A

8 papers

NM_032271.3

p.T391I

c.1172C>T

2 papers

NM_032271.3

p.K389E

c.1165A>G

3 papers

NM_032271.3

p.C388W

c.1164C>G

5 papers

NM_032271.3

p.C388Y

c.1163G>A

1 paper

NM_032271.3

p.C388S

c.1163G>C

1 paper

NM_032271.3

p.C388F

c.1163G>T

1 paper

NM_032271.3

p.C388S

c.1162T>A

2 papers

NM_032271.3

p.C388R

c.1162T>C

1 paper

NM_032271.3

p.K387Q

c.1159A>C