Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_032271.3

p.S561R

c.1681A>C

Surrounding Variants

4 papers

NM_032271.3

p.S561N

c.1682G>A

10 papers

NM_032271.3

p.S561R

c.1683C>A

10 papers

NM_032271.3

p.S561R

c.1683C>G

3 papers

NM_032271.3

p.G560D

c.1679G>A

2 papers

NM_032271.3

p.G560S

c.1678G>A

1 paper

NM_032271.3

p.G560C

c.1678G>T

2 papers

NM_032271.3

p.G559V

c.1676G>T

1 paper

NM_032271.3

p.G559R

c.1675G>C

2 papers

NM_032271.3

p.G559C

c.1675G>T

8 papers

NM_032271.3

p.Y563C

c.1688A>G

4 papers

NM_032271.3

p.S558Y

c.1673C>A

4 papers

NM_032271.3

p.S558F

c.1673C>T