Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032271.3

p.E578D

c.1734G>T

Surrounding Variants

1 paper

NM_032271.3

p.E578D

c.1734G>C

4 papers

NM_032271.3

p.L580del1

c.1738_1739delCTC

1 paper

NM_032271.3

p.E578K

c.1732G>A

2 papers

NM_032271.3

p.Y577S

c.1730A>C

5 papers

NM_032271.3

p.Y577C

c.1730A>G

1 paper

NM_032271.3

p.Y577delFs

c.1731delC

1 paper

NM_032271.3

p.Y577N

c.1729T>A

2 papers

NM_032271.3

p.Y577D

c.1729T>G

1 paper

NM_032271.3

p.H582fs

c.1744_1745fs

1 paper

NM_032271.3

p.V573F

c.1717G>T

1 paper

NM_032271.3

p.H571delFs

c.1711delC

3 papers

NM_032271.3

p.H570D

c.1708C>G