Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032271.3

p.I634S

c.1901T>G

Surrounding Variants

2 papers

NM_032271.3

p.C635_T636delFs

c.1903_1907del5

1 paper

NM_032271.3

p.T636M

c.1907C>T

1 paper

NM_032271.3

p.Q637E

c.1909C>G

6 papers

NM_032271.3

p.Q637H

c.1911G>C

6 papers

NM_032271.3

p.Q637H

c.1911G>T

1 paper

NM_032271.3

p.S629R

c.1887T>A

1 paper

NM_032271.3

p.S629R

c.1887T>G

2 papers

NM_032271.3

p.S629N

c.1886G>A

1 paper

NM_032271.3

p.S629T

c.1886G>C

1 paper

NM_032271.3

p.S629R

c.1885A>C

1 paper

NM_032271.3

p.S629G

c.1885A>G

14 papers

NM_032271.3

p.R641C

c.1921C>T