Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_032271.3

p.R653Q

c.1958G>A

Surrounding Variants

3 papers

NM_032271.3

p.R653P

c.1958G>C

1 paper

NM_032271.3

p.R653L

c.1958G>T

2 papers

NM_032271.3

p.G654D

c.1961G>A

23 papers

NM_032271.3

p.R655Q

c.1964G>A

1 paper

NM_032271.3

p.G659W

c.1975G>T

1 paper

NM_032271.3

p.T647A

c.1939A>G

2 papers

NM_032271.3

p.V646I

c.1936G>A

2 papers

NM_032271.3

p.V646L

c.1936G>C

1 paper

NM_032271.3

p.V646F

c.1936G>T

2 papers

NM_032271.3

p.S645R

c.1935T>A

2 papers

NM_032271.3

p.S645R

c.1935T>G

1 paper

NM_032271.3

p.V661G

c.1982T>G