Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.A190V

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_018965.4
p.A190V
c.569C>T
Surrounding Variants
13 papers
NM_018965.4
p.A192T
c.574G>A
1 paper
NM_018965.4
p.L188L
c.562C>T
19 papers
NM_018965.4
p.K186N
c.558G>T
1 paper
NM_018965.4
p.K186_I187insFs
c.558_559insC
18 papers
NM_018965.4
p.K186N
c.558G>C
2 papers
NM_018965.4
p.K186K
c.558G>A
1 paper
NM_018965.4
p.W194*
c.581G>A
1 paper
NM_018965.4
p.W194*
c.582G>A
1 paper
NM_018965.4
p.K186*
c.556A>T
3 papers
NM_018965.4
p.A196T
c.586G>A
1 paper
NM_018965.4
p.F183delFs
c.549delA
1 paper
NM_018965.4
p.L184fs
c.550_551fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."