Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.G166E

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_018965.4
p.G166E
c.497G>A
Surrounding Variants
3 papers
NM_018965.4
p.G166R
c.496G>A
1 paper
NM_018965.4
p.L163P
c.488T>C
1 paper
NM_018965.4
p.L163V
c.487C>G
2 papers
NM_018965.4
p.F170L
c.508T>C
7 papers
NM_018965.4
p.S162R
c.486C>G
7 papers
NM_018965.4
p.S162R
c.486C>A
2 papers
NM_018965.4
p.F170L
c.510C>G
2 papers
NM_018965.4
p.F170L
c.510C>A
7 papers
NM_018965.4
p.S162R
c.484A>C
1 paper
NM_018965.4
p.P171T
c.511C>A
1 paper
NM_018965.4
p.T173A
c.517A>G
1 paper
NM_018965.4
p.S174F
c.521C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."