Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.A118V

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_018965.4
p.A118V
c.353C>T
Surrounding Variants
10 papers
NM_018965.4
p.S116C
c.346A>T
4 papers
NM_018965.4
p.L121R
c.362T>G
1 paper
NM_018965.4
p.G115D
c.344G>A
4 papers
NM_018965.4
p.G115S
c.343G>A
1 paper
NM_018965.4
p.H114H
c.342T>C
2 papers
NM_018965.4
p.R122W
c.364A>T
1 paper
NM_018965.4
p.L121delFs
c.363delG
1 paper
NM_018965.4
p.K123E
c.367A>G
2 papers
NM_018965.4
p.V124I
c.370G>A
1 paper
NM_018965.4
p.V124G
c.371T>G
1 paper
NM_018965.4
p.S112N
c.335G>A
1 paper
NM_018965.4
p.V124V
c.372C>A
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