Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.N68K

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
12 papers
NM_018965.4
p.N68K
c.204C>G
Surrounding Variants
12 papers
NM_018965.4
p.N68K
c.204C>A
1 paper
NM_018965.4
p.L69S
c.206T>C
1 paper
NM_018965.4
p.H67fs
c.199_200fs
2 papers
NM_018965.4
p.H67delFs
c.199delG
1 paper
NM_018965.4
p.W70*
c.209G>A
2 papers
NM_018965.4
p.H67fs
c.199_200fs
1 paper
NM_018965.4
p.W70*
c.210G>A
145 papers
NM_018965.4
p.T66M
c.197C>T
1 paper
NM_018965.4
p.L71L
c.211C>T
2 papers
NM_018965.4
p.T66S
c.196A>T
2 papers
NM_018965.4
p.L72V
c.214C>G
1 paper
NM_018965.4
p.L72ins2
c.215_216ins6
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."