Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.D39E

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
15 papers
NM_018965.4
p.D39E
c.117C>A
Surrounding Variants
15 papers
NM_018965.4
p.D39E
c.117C>G
5 papers
NM_018965.4
p.D39G
c.116A>G
1 paper
NM_018965.4
p.D39N
c.115G>A
1 paper
NM_018965.4
p.M41L
c.121A>T
90 papers
NM_018965.4
p.Y38C
c.113A>G
1 paper
NM_018965.4
p.M41T
c.122T>C
1 paper
NM_018965.4
p.H43Y
c.127C>T
1 paper
NM_018965.4
p.S35F
c.104C>T
15 papers
NM_018965.4
p.W44*
c.131G>A
17 papers
NM_018965.4
p.W44*
c.132G>A
1 paper
NM_018965.4
p.V34V
c.102G>A
1 paper
NM_018965.4
p.G45E
c.134G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."