Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.Q25*

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_018965.4
p.Q25*
c.73C>T
Surrounding Variants
1 paper
NM_018965.4
p.G26A
c.77G>C
2 papers
NM_018965.4
p.V23L
c.67G>T
2 papers
NM_018965.4
p.V23L
c.67G>C
5 papers
NM_018965.4
p.V27M
c.79G>A
1 paper
NM_018965.4
p.V27E
c.80T>A
11 papers
NM_018965.4
p.A28V
c.83C>T
1 paper
NM_018965.4
p.T21T
c.63C>G
1 paper
NM_018965.4
p.A28E
c.83C>A
1 paper
NM_018965.4
p.N20K
c.60C>A
2 papers
NM_018965.4
p.N20D
c.58A>G
9 papers
NM_018965.4
p.S31F
c.92C>T
1 paper
NM_018965.4
p.S31_L32insFs
c.93_94insG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."