Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003141.4

p.F420_Y421del1

c.1260_1262delTAG

Surrounding Variants

1 paper

NM_003141.4

p.S432F

c.1295C>T

1 paper

NM_003141.4

p.G440R

c.1318G>C

1 paper

NM_003141.4

p.G440R

c.1318G>A

1 paper

NM_003141.4

p.P403T

c.1207C>A

1 paper

NM_003141.4

p.R443W

c.1327C>T

3 papers

NM_003141.4

p.F446I

c.1336T>A

1 paper

NM_003141.4

p.P448L

c.1343C>T

1 paper

NM_003141.4

p.Y393F

c.1178A>T

1 paper

NM_003141.4

p.A390V

c.1169C>T

2 papers

NM_003141.4

p.K455E

c.1363A>G

1 paper

NM_003141.4

p.Y388F

c.1163A>T

1 paper

NM_003141.4

p.C463F

c.1388G>T