Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003141.4

p.R234*

c.700C>T

Surrounding Variants

1 paper

NM_003141.4

p.L232Q

c.695T>A

1 paper

NM_003141.4

p.L232L

c.694C>T

1 paper

NM_003141.4

p.H237D

c.709C>G

1 paper

NM_003141.4

p.L241M

c.721C>A

1 paper

NM_003141.4

p.Q226L

c.677A>T

1 paper

NM_003141.4

p.L243M

c.727C>A

1 paper

NM_003141.4

p.A224V

c.671C>T

1 paper

NM_003141.4

p.K217R

c.650A>G

1 paper

NM_003141.4

p.K214R

c.641A>G

1 paper

NM_003141.4

p.E206K

c.616G>A

1 paper

NM_003141.4

p.R205W

c.613A>T

1 paper

NM_003141.4

p.E201A

c.602A>C