Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003141.4

p.K105N

c.315A>T

Surrounding Variants

1 paper

NM_003141.4

p.K105R

c.314A>G

1 paper

NM_003141.4

p.C103Y

c.308G>A

1 paper

NM_003141.4

p.F102C

c.305T>G

2 papers

NM_003141.4

p.L110P

c.329T>C

1 paper

NM_003141.4

p.R98I

c.293G>T

1 paper

NM_003141.4

p.S117Y

c.350C>A

1 paper

NM_003141.4

p.R118Q

c.353G>A

1 paper

NM_003141.4

p.R121C

c.361C>T

1 paper

NM_003141.4

p.R121H

c.362G>A

1 paper

NM_003141.4

p.E90K

c.268G>A

2 papers

NM_003141.4

p.G89E

c.266G>A

1 paper

NM_003141.4

p.D122N

c.364G>A