Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003141.4

p.V50I

c.148G>A

Surrounding Variants

1 paper

NM_003141.4

p.G47R

c.139G>C

1 paper

NM_003141.4

p.G47R

c.139G>A

1 paper

NM_003141.4

p.C54Y

c.161G>A

1 paper

NM_003141.4

p.K45R

c.134A>G

1 paper

NM_003141.4

p.K45E

c.133A>G

3 papers

NM_003141.4

p.R57C

c.169C>T

2 papers

NM_003141.4

p.R57H

c.170G>A

1 paper

NM_003141.4

p.C39Y

c.116G>A

1 paper

NM_003141.4

p.C39G

c.115T>G

1 paper

NM_003141.4

p.C39fs

c.115_116fs

1 paper

NM_003141.4

p.K61R

c.182A>G

2 papers

NM_003141.4

p.E38G

c.113A>G