Varaico: Literature-Extracted Genetic Variants

Gene:TRIM31
Variant:p.E421K

TRIM31

41 papers

RefSeq Summary

This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing ...

Pfam Domains

zf-C3HC4_4aa 16–56UCSCzinc finger of C3HC4-type, RING
zf-B_boxaa 90–131UCSCB-box zinc finger

Gene Aliases

HGNC Name

tripartite motif containing 31

HGNC Alias Symbol

HCGI

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_007028.5
p.E421K
c.1261G>A
Surrounding Variants
1 paper
NM_007028.5
p.T413I
c.1238C>T
4 papers
NM_007028.5
p.E410*
c.1228G>T
1 paper
NM_007028.5
p.D397G
c.1190A>G
2 papers
NM_007028.5
p.L361fs
c.1081_1082fs
1 paper
NM_007028.5
p.L361delFs
c.1081_1082delAG
1 paper
NM_007028.5
p.D304Y
c.910G>T
1 paper
NM_007028.5
p.D300V
c.899A>T
1 paper
NM_007028.5
p.A279G
c.836C>G
1 paper
NM_007028.5
p.P265L
c.794C>T
1 paper
NM_007028.5
p.R256Splc
c.767+3A>G
1 paper
NM_007028.5
p.Q245R
c.734A>G
1 paper
NM_007028.5
p.P242Q
c.725C>A
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