Varaico: Literature-Extracted Genetic Variants

TRIM71

102 papers

RefSeq Summary

The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase tran...

Pfam Domains

zf-C3HC4aa 50–94UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 273–314UCSCB-box zinc finger

Filaminaa 481–577UCSCFilamin/ABP280 repeat

NHLaa 606–633UCSCNHL repeat

NHLaa 653–680UCSCNHL repeat

NHLaa 700–727UCSCNHL repeat

Gene Aliases

HGNC Name

tripartite motif containing 71

HGNC Alias Symbols

LIN41; LIN-41

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001039111.3

p.L288L

c.864G>C

Surrounding Variants

1 paper

NM_001039111.3

p.Y289N

c.865T>A

1 paper

NM_001039111.3

p.Q315*

c.943C>T

1 paper

NM_001039111.3

p.R322Q

c.965G>A

1 paper

NM_001039111.3

p.L329P

c.986T>C

3 papers

NM_001039111.3

p.Q334R

c.1001A>G

1 paper

NM_001039111.3

p.R336delFs

c.1007delG

1 paper

NM_001039111.3

p.Q340_L341Splc

c.1020+1G>C

1 paper

NM_001039111.3

p.Q340_L341Splc

c.1020+6C>T