Varaico: Literature-Extracted Genetic Variants

TRIM71

102 papers

RefSeq Summary

The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase tran...

Pfam Domains

zf-C3HC4aa 50–94UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 273–314UCSCB-box zinc finger

Filaminaa 481–577UCSCFilamin/ABP280 repeat

NHLaa 606–633UCSCNHL repeat

NHLaa 653–680UCSCNHL repeat

NHLaa 700–727UCSCNHL repeat

Gene Aliases

HGNC Name

tripartite motif containing 71

HGNC Alias Symbols

LIN41; LIN-41

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001039111.3

p.R496C

c.1486C>T

Surrounding Variants

1 paper

NM_001039111.3

p.R496H

c.1487G>A

1 paper

NM_001039111.3

p.K495Q

c.1483A>C

1 paper

NM_001039111.3

p.K488R

c.1463A>G

1 paper

NM_001039111.3

p.F505L

c.1513T>C

1 paper

NM_001039111.3

p.F505L

c.1515C>A

1 paper

NM_001039111.3

p.F505L

c.1515C>G

2 papers

NM_001039111.3

p.R517C

c.1549C>T

1 paper

NM_001039111.3

p.S525P

c.1573T>C

1 paper

NM_001039111.3

p.D465Y

c.1393G>T

1 paper

NM_001039111.3

p.P463insFs

c.1387dupC

1 paper

NM_001039111.3

p.T462fs

c.1384_1385fs

1 paper

NM_001039111.3

p.V459_A467del9

c.1375_1400del27