Varaico: Literature-Extracted Genetic Variants

TRPC4

112 papers

RefSeq Summary

This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by G...

Pfam Domains

Ank_2aa 37–127UCSCAnkyrin repeats (3 copies)

Ankaa 142–171UCSCAnkyrin repeat

TRP_2aa 176–238UCSCTransient receptor ion channel II

Ion_transaa 364–632UCSCIon transport protein

Gene Aliases

HGNC Name

transient receptor potential cation channel subfamily C member 4

HGNC Alias Symbols

HTRP4; TRP4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016179.4

p.F848V

c.2542T>G

Surrounding Variants

1 paper

NM_016179.4

p.D841A

c.2522A>C

1 paper

NM_016179.4

p.D841Y

c.2521G>T

1 paper

NM_016179.4

p.R834T

c.2501G>C

1 paper

NM_016179.4

p.R889Q

c.2666G>A

2 papers

NM_016179.4

p.R894Q

c.2681G>A

1 paper

NM_016179.4

p.G785C

c.2353G>T

1 paper

NM_016179.4

p.K758Q

c.2272A>C

1 paper

NM_016179.4

p.L753S

c.2258T>C

1 paper

NM_016179.4

p.H949R

c.2846A>G

1 paper

NM_016179.4

p.S956I

c.2867G>T

3 papers

NM_016179.4

p.I957V

c.2869A>G

2 papers

NM_016179.4

p.Y959F

c.2876A>T