Varaico: Literature-Extracted Genetic Variants

TRRAP

457 papers

RefSeq Summary

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexe...

Pfam Domains

Tra1_centralaa 276–883UCSCTra1 HEAT repeat central region

Tra1_ringaa 893–2689UCSCTra1 HEAT repeat ring region

FATaa 2856–3200UCSCFAT domain

PI3_PI4_kinaseaa 3548–3797UCSCPhosphatidylinositol 3- and 4-kinase

Gene Aliases

HGNC Name

transformation/transcription domain associated protein

HGNC Alias Symbols

TR-AP; PAF400; Tra1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 592 variants

30 papers

NM_001375524.1

p.S722F

c.2165C>T

8 papers

NM_001375524.1

p.R816W

c.2446C>T

8 papers

NM_001375524.1

p.A1043T

c.3127G>A

5 papers

NM_001375524.1

p.R696H

c.2087G>A

4 papers

NM_001375524.1

p.R171C

c.511C>T

4 papers

NM_001375524.1

p.E2750D

c.8250G>C

4 papers

NM_001375524.1

p.E2750D

c.8250G>T

3 papers

NM_001375524.1

p.I295F

c.883A>T

3 papers

NM_001375524.1

p.A482G

c.1445C>G

3 papers

NM_001375524.1

p.L805F

c.2413C>T

3 papers

NM_001375524.1

p.E1106K

c.3316G>A

3 papers

NM_001375524.1

p.E1284Q

c.3850G>C