Varaico: Literature-Extracted Genetic Variants

TRRAP

457 papers

RefSeq Summary

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexe...

Pfam Domains

Tra1_centralaa 276–883UCSCTra1 HEAT repeat central region

Tra1_ringaa 893–2689UCSCTra1 HEAT repeat ring region

FATaa 2856–3200UCSCFAT domain

PI3_PI4_kinaseaa 3548–3797UCSCPhosphatidylinositol 3- and 4-kinase

Gene Aliases

HGNC Name

transformation/transcription domain associated protein

HGNC Alias Symbols

TR-AP; PAF400; Tra1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001375524.1

p.R171C

c.511C>T

Surrounding Variants

1 paper

NM_001375524.1

p.I179T

c.536T>C

1 paper

NM_001375524.1

p.E181K

c.541G>A

1 paper

NM_001375524.1

p.P186S

c.556C>T

1 paper

NM_001375524.1

p.M189I

c.567G>A

1 paper

NM_001375524.1

p.M189I

c.567G>C

1 paper

NM_001375524.1

p.M189I

c.567G>T

1 paper

NM_001375524.1

p.V200D

c.599T>A

1 paper

NM_001375524.1

p.E203K

c.607G>A

1 paper

NM_001375524.1

p.R204C

c.610C>T

1 paper

NM_001375524.1

p.E208K

c.622G>A

1 paper

NM_001375524.1

p.R210Q

c.629G>A

1 paper

NM_001375524.1

p.T211K

c.632C>A