Varaico: Literature-Extracted Genetic Variants

TRRAP

457 papers

RefSeq Summary

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexe...

Pfam Domains

Tra1_centralaa 276–883UCSCTra1 HEAT repeat central region

Tra1_ringaa 893–2689UCSCTra1 HEAT repeat ring region

FATaa 2856–3200UCSCFAT domain

PI3_PI4_kinaseaa 3548–3797UCSCPhosphatidylinositol 3- and 4-kinase

Gene Aliases

HGNC Name

transformation/transcription domain associated protein

HGNC Alias Symbols

TR-AP; PAF400; Tra1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001375524.1

p.I281T

c.842T>C

Surrounding Variants

1 paper

NM_001375524.1

p.K286N

c.858A>C

1 paper

NM_001375524.1

p.K286N

c.858A>T

1 paper

NM_001375524.1

p.L288M

c.862T>A

1 paper

NM_001375524.1

p.N273S

c.818A>G

3 papers

NM_001375524.1

p.I295F

c.883A>T

1 paper

NM_001375524.1

p.I258V

c.772A>G

1 paper

NM_001375524.1

p.P252S

c.754C>T

1 paper

NM_001375524.1

p.Y239_K240delFs

c.717_720del4

1 paper

NM_001375524.1

p.L225F

c.675G>C

1 paper

NM_001375524.1

p.L225F

c.675G>T

1 paper

NM_001375524.1

p.L220F

c.658C>T

1 paper

NM_001375524.1

p.P216L

c.647C>T