Varaico: Literature-Extracted Genetic Variants

TRRAP

457 papers

RefSeq Summary

This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexe...

Pfam Domains

Tra1_centralaa 276–883UCSCTra1 HEAT repeat central region

Tra1_ringaa 893–2689UCSCTra1 HEAT repeat ring region

FATaa 2856–3200UCSCFAT domain

PI3_PI4_kinaseaa 3548–3797UCSCPhosphatidylinositol 3- and 4-kinase

Gene Aliases

HGNC Name

transformation/transcription domain associated protein

HGNC Alias Symbols

TR-AP; PAF400; Tra1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001375524.1

p.F714L

c.2140T>C

Surrounding Variants

1 paper

NM_001375524.1

p.F714L

c.2142C>A

1 paper

NM_001375524.1

p.F714L

c.2142C>G

1 paper

NM_001375524.1

p.V717_S720del4

c.2149_2159del12

1 paper

NM_001375524.1

p.V717V

c.2151C>T

1 paper

NM_001375524.1

p.S720F

c.2159C>T

2 papers

NM_001375524.1

p.S707P

c.2119T>C

30 papers

NM_001375524.1

p.S722F

c.2165C>T

1 paper

NM_001375524.1

p.S722S

c.2166C>T

1 paper

NM_001375524.1

p.E727V

c.2180A>T

5 papers

NM_001375524.1

p.R696H

c.2087G>A

1 paper

NM_001375524.1

p.R696C

c.2086C>T

1 paper

NM_001375524.1

p.D695H

c.2083G>C