Varaico: Literature-Extracted Genetic Variants

TSEN34

51 papers

RefSeq Summary

This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prim...

Pfam Domains

TSEN34_Naa 2–71UCSCTSEN34-like, N-terminal domain

tRNA_int_endoaa 217–301UCSCtRNA intron endonuclease, catalytic C-terminal domain

Gene Aliases

HGNC Name

tRNA splicing endonuclease subunit 34

HGNC Previous Symbol

LENG5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001077446.4

p.A307S

c.919G>T

Surrounding Variants

1 paper

NM_001077446.4

p.D296E

c.888T>A

1 paper

NM_001077446.4

p.D296E

c.888T>G

3 papers

NM_001077446.4

p.P293L

c.878C>T

1 paper

NM_001077446.4

p.R279C

c.835C>T

1 paper

NM_001077446.4

p.L274M

c.820C>A

1 paper

NM_001077446.4

p.T268I

c.803C>T

1 paper

NM_001077446.4

p.F254L

c.762C>A

1 paper

NM_001077446.4

p.F254L

c.762C>G

1 paper

NM_001077446.4

p.F254L

c.760T>C

1 paper

NM_001077446.4

p.P248L

c.743C>T

1 paper

NM_001077446.4

p.G238D

c.713G>A

1 paper

NM_001077446.4

p.R225K

c.674G>A