tetraspanin 4

TM4SF7

NAG-2

TSPAN-4

TETRASPAN

transmembrane 4 superfamily member 7

Tetraspanin-4

Novel antigen 2

Transmembrane 4 superfamily member 7

Tspan-4

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

TSPAN4

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol