Varaico: Literature-Extracted Genetic Variants

TTF2

1,233 papers

RefSeq Summary

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activ...

Pfam Domains

Zn_ribbon_GRFaa 4–42UCSCGRF zinc finger

SNF2-rel_domaa 573–932UCSCSNF2-related domain

Helicase_Caa 991–1106UCSCHelicase conserved C-terminal domain

Gene Aliases

HGNC Name

transcription termination factor 2

HGNC Alias Symbols

HuF2; ZGRF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003594.4

p.M1T

c.2T>C

Surrounding Variants

1 paper

NM_003594.4

p.M1K

c.2T>A

1 paper

NM_003594.4

p.M1Fs

c.3delinsCATTTGGGCTCCTCATTTGGFs

2 papers

NM_003594.4

p.M1insFs

c.2dupT

1 paper

NM_003594.4

p.M1V

c.1A>G

4 papers

NM_003594.4

p.M1I

c.3G>A

1 paper

NM_003594.4

p.M1I

c.3G>C

3 papers

NM_003594.4

p.M1I

c.3G>T

2 papers

NM_003594.4

p.E2K

c.4G>A

1 paper

NM_003594.4

p.E2Q

c.4G>C

1 paper

NM_003594.4

p.E2G

c.5A>G

3 papers

NM_003594.4

p.E3K

c.7G>A

1 paper

NM_003594.4

p.E3Q

c.7G>C